Selected Publications



Robinson, G.C., Bason, J.V., Montgomery, M.G., Fearnley, I.M., Mueller, D.M., Leslie, A.G.W.,  and Walker, J.E. The structure of F1-ATPase from Saccharomyces cerevisiae inhibited by its regulatory protein IF1.  (2013) Open Biol. 3: 120164.


Symersky, J., Osowski, D., Walters, D.E. (2012) Oligomycin frames a common drug binding site in the ATP synthase.  Proc. Natl. Acad. Sci, USA, 109: 13961-13965. (Chosen by Faculty of 1000:


Symersky, J., Pagadala, V., Osowski, D., Krah, A., Meier, T., Faraldo-Gómez, J.D., Mueller, D.M., (2012) Structure of the c10 ring of the yeast mitochondrial ATP synthase in the open conformation Nat. Struc. Molec. Biol. 19: 485-491. (The results of this paper was summarized in “Research Highlights” in the August issue of Biopolymers, 97 (8), iii-iv, 2012 and was also highlighted by GM/CA-CAT at the Advance Photon Source in their annual report to the NIH. To quote Prof. Janet Smith, Scientific Director and Dr. Robert Fischetti, Group Leader of GM/CA, “…and we would like to highlight this paper as a significant contribution from data collected at GM/CA@APS. … The highlights will be used in our annual report to the NIH, and posted on the GM/CA@APS website.”)


Pagadala, V., Vistain, L., Symersky, J., and Mueller, D.M. (2011) Characterization Of The Mitochondrial ATP Synthase From Yeast Saccharomyces cerevisiae, J. Bioener. Biomemb. 43, 333-347. PMCID: in process


Little, M.A, Steel, B.C., Bai, F., Sowa, Y., Bilyard, T., Mueller, D.M., Berry, R.M.Jones, N.S (2011) Steps and bumps: precision extraction of discrete states of molecular machines, Biophysical Journal, 101(2):477-485. PMCID: PMC3136774


Arsenieva, D., Symersky, J., Wang, Y., Pagadala, V., and Mueller, D.M. (2010) Crystal Structure of mutant forms of the yeast F1ATPase reveal two modes of uncoupling. J. Biol. Chem. 285: 36561-36569. PMCID: PMC2978584


Shen,H., Walters, D.E., and Mueller, D.M. (2008)  Introduction of The Chloroplast Redox Regulatory Region In the Yeast ATP Synthase Impairs Cytochrome Oxidase, J. Biol. Chem. 283: 32937-32943. PMCID: PMC2583308


Kabaleeswaran, V., Shen, H., Symersky, J., Walker, JE, Leslie, AGW, Mueller, D.M., (2009)  Asymmetric structure of the yeast F1 ATPase in the absence of bound nucleotides, J. Biol Chem.  284: 10546-10551. PMCID: PMC2667741


Wang, Y., Singh, U., and Mueller, D.M. (2007) Mitochondrial Genome Integrity Mutations Uncouple the Yeast Saccharomyces cerevisiae ATP Synthase J. Biol. Chem. 282: 8228-8236. PMID:17244612


Kabaleeswaran V, Puri N, Walker JE, Leslie AG, Mueller DM. (2006) Novel features of the rotary catalytic mechanism in the structure of the yeast F1 ATPase. EMBO J., 25, 5433-5442. PMCID: PMC1636620


Puri N, Lai-Zhang J, Meier S, Mueller DM., (2005) Expression of bovine F1-ATPase with functional complementation in yeast Saccharomyces cerevisiae. J. Biol. Chem. 280:22418-22424. PMID:15817482


Corvest V, Sigalat C, Venard R, Falson P, Mueller DM, Haraux F., (2005) The binding mechanism of the yeast F1-ATPase inhibitory peptide. Role of catalytic intermediates and enzyme turnover. J. Biol. Chem., 280: 9927-9936. PMID:15640141


Mueller DM, Puri N, Kabaleeswaran V, Terry C, Leslie AG, Walker JE. (2004) Crystallization and preliminary crystallographic studies of the mitochondrial F1-ATPase from the yeast Saccharomyces cerevisiae. Acta Crystallogr D Biol Crystallogr. 60(Pt 8). 1441-1444. PMID:15272171


Paumard, P., Vaillier, J., Coulary, B., Schaeffer, J., Soubannier, V., Mueller, D. M., Brethes, D., di Rago, J. P., and Velours, J. (2002) The ATP synthase is involved in generating mitochondrial cristae morphology EMBO J 21, 221-30. PMCID: PMC125827


Velours, J., Vaillier, J.,  Paumard, P., Soubannier, V., Lai-Zhang, J., and Mueller, D.M., (2001)  Bovine coupling factor 6, with just 14.5% shared  identity, replaces subunit h in the yeast Saccharomyces cerevisiae ATP synthase. J. Biol. Chem., 276:8602-8607. PMID:11083870


Xiao, Y., Metzl, M. and Mueller, D.M. (2000) Partial uncoupling of the mitochondrial membrane by a heterozygous null mutation in the gene encoding the gamma or delta-subunit of the yeast mitochondrial ATPase J. Biol. Chem.  275: 6963-6968. PMID:10702258